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1.
Artigo em Inglês | MEDLINE | ID: mdl-37015621

RESUMO

Photographs taken through a glass window are susceptible to disturbances due to reflection. Therefore, single image reflection removal is crucial to image quality enhancement. In this paper, a novel learning architecture that can address this ill-posed problem is proposed. First, a novel reflection removal pipeline was designed to reconstruct the missing information caused by the camera imaging process using the proposed missing recovery network. Second, to address the issues in existing reflection removal strategies, we revisit several auxiliary priors and integrate them by defining an energy function. To solve the energy function, a convolutional neural network-based optimization scheme was proposed. Finally, we investigated the dark channel responses of reflection and clean images and found an interesting way to distinguish between these two types of images. We prove this property mathematically and propose a novel loss function called dark channel loss to improve performance. Experiments show that the proposed method outperforms state-of-the-art reflection removal methods both quantitatively and qualitatively.

2.
Hum Cell ; 33(4): 990-1005, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32617892

RESUMO

Orchestrated control of multiple overlapping and sequential processes is required for the maintenance of epidermal homeostasis and the response to and recovery from a variety of skin insults. Previous studies indicate that membrane-associated serine protease matriptase and prostasin play essential roles in epidermal development, differentiation, and barrier formation. The control of proteolysis is a highly regulated process, which depends not only on gene expression but also on zymogen activation and the balance between protease and protease inhibitor. Subcellular localization can affect the accessibility of protease inhibitors to proteases and, thus, also represents an integral component of the control of proteolysis. To understand how membrane-associated proteolysis is regulated in human skin, these key aspects of matriptase and prostasin were determined in normal and injured human skin by immunohistochemistry. This staining shows that matriptase is expressed predominantly in the zymogen form at the periphery of basal and spinous keratinocytes, and prostasin appears to be constitutively activated at high levels in polarized organelle-like structures of the granular keratinocytes in the adjacent quiescent skin. The membrane-associated proteolysis appears to be elevated via an increase in matriptase zymogen activation and prostasin protein expression in areas of skin recovering from epidermal insults. There was no noticeable change observed in other regulatory aspects, including the expression and tissue distribution of their cognate inhibitors HAI-1 and HAI-2. This study reveals that the membrane-associated proteolysis may be a critical epidermal mechanism involved in responding to, and recovering from, damage to human skin.


Assuntos
Regulação da Expressão Gênica no Desenvolvimento , Expressão Gênica , Serina Endopeptidases/genética , Serina Endopeptidases/metabolismo , Fenômenos Fisiológicos da Pele/genética , Pele/lesões , Cicatrização/genética , Cicatrização/fisiologia , Ferimentos e Lesões/genética , Ferimentos e Lesões/metabolismo , Células Cultivadas , Precursores Enzimáticos/genética , Precursores Enzimáticos/metabolismo , Humanos , Glicoproteínas de Membrana/genética , Glicoproteínas de Membrana/metabolismo , Proteínas Secretadas Inibidoras de Proteinases/genética , Proteínas Secretadas Inibidoras de Proteinases/metabolismo , Proteólise , Serina Endopeptidases/fisiologia , Pele/metabolismo
3.
Materials (Basel) ; 12(9)2019 May 09.
Artigo em Inglês | MEDLINE | ID: mdl-31075838

RESUMO

This study assessed the use of volcanic mud collected from southern Taiwan and the incorporation of paper sludge for manufacturing lightweight aggregate (LWA). The firing process of the raw materials and related sintering mechanisms, including sintering temperature and time, were investigated. LWA was manufactured at sintering temperatures ranging from 950 to 1275 °C with soaking times from 2 to 15 min, and preheating temperatures ranged between 500 and 700 °C with soaking times from 5 to 15 min. Using volcanic mud and mixed sludge (volcanic mud with added paper sludge) resulted in the successful manufacture of various qualified LWAs with particle density ranging from 973 to 1950 g/cm3, water absorption from 6.2 to 20.0%, and crushing strength from 2.2 to 15.8 MPa.

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